<b>Multi-step reaction with 9 steps<br /> </b>1: 87 percent / bromine / methanol / 0.5 h / Ambient temperature<br />2: 84 percent<br />3: 86 percent / 2N sodium hydroxide / H₂O; CH₂Cl₂ <br />5: N-methylmorpholine N-oxide, selenium dioxide<br />6: imidazole / dimethylformamide<br />7: 33 percent / NaBH₄, CeCl₃*6H₂O / methanol / further reag.: (S)-BINAL-H<br />8: anthracene, triethylamine / toluene / 1 h / 20 &deg;C / Irradiation<br />9: 73 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.83 h / 60 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 8 steps<br /> </b>1: 84 percent<br />2: 86 percent / 2N sodium hydroxide / H₂O; CH₂Cl₂ <br />4: N-methylmorpholine N-oxide, selenium dioxide<br />5: imidazole / dimethylformamide<br />6: 33 percent / NaBH₄, CeCl₃*6H₂O / methanol / further reag.: (S)-BINAL-H<br />7: anthracene, triethylamine / toluene / 1 h / 20 &deg;C / Irradiation<br />8: 73 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.83 h / 60 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 6 steps<br /> </b>2: N-methylmorpholine N-oxide, selenium dioxide<br />3: imidazole / dimethylformamide<br />4: 33 percent / NaBH₄, CeCl₃*6H₂O / methanol / further reag.: (S)-BINAL-H<br />5: anthracene, triethylamine / toluene / 1 h / 20 &deg;C / Irradiation<br />6: 73 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.83 h / 60 &deg;C<br /> <br /> &nbsp;