1: 1-(4-chloro-3-(trifluromethyl)phenyl)-3-(4-hydroxyphenyl)urea With potassium tert-butylate in N,N-dimethyl-formamide T=20°C; 2 - 3 h; 2: 4-chloro-N-methyl-2-pyridinecarboxamide in N,N-dimethyl-formamide T=60 - 70°C; 2 - 3 h; Product distribution / selectivity;

1: 1-(4-chloro-3-(trifluromethyl)phenyl)-3-(4-hydroxyphenyl)urea With potassium tert-butylate in N,N-dimethyl-formamide 3 h; 2: 4-chloro-N-(methyl-d3)picolinamide With potassium carbonate T=80°C; 1.5 h;