1,2,3-苯并三唑-5-羧酸甲酯合成路线 （共 5 条）
反应条件
sulfuric acid 4 h; Heating;
参考文献
Katritzky; Ji; Fan; Delprato
Synthetic Communications, 1993 , vol. 23, # 14 p. 2019 - 2025
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 4 h;
参考文献
UNIVERSITY HEALTH NETWORK
Patent: WO2009/79767 A1, 2009 ;
Location in patent: Page/Page column 83 ;
WO 2009/079767 A1
反应条件
sodium hydroxide T=37°C; various temp.; also in phosphate buffer (pH 7.4) or enzyme catalyzed (microsomal hog liver esterase); energy of activation; Rate constantThermodynamic data;
参考文献
Jacobi, Sylvia; Hoffmann, Hermann
Archiv der Pharmazie (Weinheim, Germany), 1989 , vol. 322, p. 89 - 92
反应条件
hydrolysis by rat liver microsomes, inhibition of the microsomal esterases with paraoxone; further esters, also of the corresponding 1H-benzotriazole-7-carboxylic acid;
参考文献
Jacobi; Hoffmann
Archiv der Pharmazie, 1990 , vol. 323, # 10 p. 825 - 827
反应条件
1: 80 percent / lithium aluminum hydride / tetrahydrofuran / 4 h / 20 °C
2: 90 percent / pyridinium dichromate / acetone / 4 h / 20 °C
View Scheme
参考文献
Krasavin, Mikhail; Pershin, Dmitry G.; Larkin, Denis; Kravchenko, Dmitry
Synthetic Communications, 2005 , vol. 35, # 19 p. 2587 - 2595
