5-氨基-3-甲基-1-苯基吡唑合成路线 （共 55 条）
反应条件
1: With hydrogenchloride in water 0.5 h; Heating / reflux; 2: With sodium hydroxide in water T=0°C;
参考文献
UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ
Patent: WO2006/92032 A2, 2006 ;
Location in patent: Page/Page column 15 ;
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 14 p. 2994 - 3008
反应条件
hydrogenchloride 4 h; Heating;
参考文献
Ganesan, Arasu; Heathcock, Clayton H.
Journal of Organic Chemistry, 1993 , vol. 58, # 22 p. 6155 - 6157
反应条件
1: aniline With hydrogenchloride; sodium nitrite in water T=-2 - 0°C; 1 h; Green chemistry; 2: With ascorbic acid powder in water T=-2 - 0°C; Green chemistry; 3: 3-aminocrotononitrile in water T=45 - 90°C; Green chemistry;
参考文献
Marinozzi, Maura; Marcelli, Gloria; Carotti, Andrea; Natalini, Benedetto
RSC Advances, 2014 , vol. 4, # 14 p. 7019 - 7023
参考文献
Journal of the American Chemical Society, , vol. 81, p. 2452,2455
参考文献
Journal of the American Chemical Society, , vol. 81, p. 2452,2455
反应条件
in hydrogenchloride 3 h; Heating;
参考文献
Lahoti, Rajgopal J.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 6 p. 490 - 491
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 79, p. 47
反应条件
1: 60 percent / toluene / 20 h / Heating 2: 30 percent / diethyl ether / 24 h 3: 1.) 20percent KOH / 1.) H2O, EtOH, reflux, 10 h; 2.) neat (solid), 200 deg C, 15 min View Scheme
参考文献
Farmaco (Societa chimica italiana : 1989), , vol. 44, # 9 p. 809 - 818
反应条件
1: 30 percent / diethyl ether / 24 h 2: 1.) 20percent KOH / 1.) H2O, EtOH, reflux, 10 h; 2.) neat (solid), 200 deg C, 15 min View Scheme
参考文献
Farmaco (Societa chimica italiana : 1989), , vol. 44, # 9 p. 809 - 818
