3,4-二甲氧基苯乙酮合成路线 （共 188 条）
反应条件
sodium hypochlorite; sodium hydroxide in water T=40°C; 1 h; TemperatureConcentration;
参考文献
Organic Process Research and Development, , vol. 3, # 5 p. 341 - 346
参考文献
Chemische Berichte, , vol. 24, p. 2867
反应条件
in acetic acid 20 h; Heating;
参考文献
Bianchi, Mario; Butti, Alina; Christidis, Yani; Perronnet, Jacques; Barzaghi, Fernando; et al.
European Journal of Medicinal Chemistry, 1988 , vol. 23, p. 45 - 52
反应条件
FibreCatTM 1000-D7; sodium t-butanolate in tetrahydrofuran T=85°C; 6 h;
参考文献
Churruca, Fatima; SanMartin, Raul; Carril, Monica; Tellitu, Imanol; Dominguez, Esther
Tetrahedron, 2004 , vol. 60, # 10 p. 2393 - 2408
反应条件
hydrogen bromide 3 h; Heating;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 3 p. 186 - 188
反应条件
sulfuric acid T=65°C; 20 h;
参考文献
Rosiak, Anna; Frey, Wolfgang; Christoffers, Jens
European Journal of Organic Chemistry, 2006 , # 17 p. 4044 - 4054
反应条件
1: (isoPrO)4Ti / 3 h / 80 °C 2: NaBH4 / methanol / 1 h / Ambient temperature 3: 94 percent / Ac2O / 1 h / 70 °C 4: 94 percent / NaIO4 / H2O; methanol / Ambient temperature 5: 96 percent / TFAA / benzene / 20 h / Ambient temperature 6: 88 percent / NaBH4, NiCl2*6H2O / methanol; tetrahydrofuran / 0.5 h / Ambient temperature 7: 91 percent / aq. NaOH / ethanol / 5 h / Heating View Scheme
参考文献
Shinohara, Tatsumi; Takeda, Akira; Toda, Jun; Terasawa, Noriyo; Sano, Takehiro
Heterocycles, 1997 , vol. 46, # 1 p. 555 - 565
反应条件
1: sodium; alcohol 2: diethyl ether; CaCl2; hydrogen chloride / 0 °C 3: pyridine View Scheme
参考文献
Mannich
Archiv der Pharmazie (Weinheim, Germany), 1910 , vol. 248, p. 143
Chem. Zentralbl., 1909 , vol. 80, # I p. 923
反应条件
1: |Heating 2: sodium hydrogencarbonate; water / methanol / 40 °C View Scheme
参考文献
Yuan, Changxia; Liang, Yong; Hernandez, Taylor; Berriochoa, Adrian; Houk, Kendall N.; Siegel, Dionicio
Nature, 2013 , vol. 499, # 7457 p. 192 - 196
反应条件
1: aqueous nitric acid; sulfuric acid / -3 °C 2: iron; aq.-ethanolic acetic acid 4: nitric acid; acetic acid / <-10 5: aq.-ethanolic hydrochloric acid View Scheme
参考文献
Simpson
Journal of the Chemical Society, 1946 , p. 96
