3,4-二甲氧基苯乙酮合成路线 （共 188 条）
反应条件
in ethanol
5 h; Reflux;
参考文献
Hosny, Mona A.; El-Sayed, Taghreed H.; El-Sawi, Emtithal A.
E-Journal of Chemistry, 2012 , vol. 9, # 3 p. 1276 - 1287
反应条件
sodium hydroxide in methanol
10 h; Ambient temperature;
参考文献
Wattanasin, Sompong; Murphy, William S.
Synthesis, 1980 , # 8 p. 647 - 650
反应条件
sodium hydride in tetrahydrofuran
5 h; Heating;
参考文献
Pericas, Lex; Shafir, Alexandr; Vallribera, Adelina
Organic Letters, 2013 , vol. 15, # 7 p. 1448 - 1451
反应条件
sodium hydroxide; potassium borohydride
4 h; Heating;
参考文献
Dem'yanovich, V.M.; Khlebnikov, V.A.
Russian Journal of Organic Chemistry, 1994 , vol. 30, # 2 p. 255 - 259
Zhurnal Organicheskoi Khimii, 1994 , vol. 30, # 2 p. 243 - 247
反应条件
1: NaBH4 / methanol; H2O / 3 h / Heating
2: 100 percent / H2SO4 / 4 h / Heating
View Scheme
参考文献
Svenson, Doug; Kadla, John F.; Chang, Hou-Min; Jameel, Hasan
Canadian Journal of Chemistry, 2002 , vol. 80, # 7 p. 761 - 766
反应条件
1: 0.05 g / hydrobromic acid / 3 h / Heating
2: K2CO3
View Scheme
参考文献
Ahluwalia, V. K.; Kapur, Kanchan; Manchanda, Saroj
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 3 p. 186 - 188
反应条件
sodium hydrogencarbonate; lithium diisopropyl amide in water; ethyl acetate
参考文献
Celgene Corporation
Patent: US6429221 B1, 2002 ;
反应条件
1: selenium dioxide / dioxane; H2O / 40 h / Heating
2: 100 °C / 23 Torr
3: tetrahydrofuran / Ambient temperature
View Scheme
参考文献
Tada, Masaru; Hamazaki, Hirohide; Hirano, Hideki
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 12 p. 3865 - 3869
反应条件
T=95°C; P=50 Torr; 3 h;
参考文献
Bianchi, Mario; Butti, Alina; Christidis, Yani; Perronnet, Jacques; Barzaghi, Fernando; et al.
European Journal of Medicinal Chemistry, 1988 , vol. 23, p. 45 - 52
反应条件
potassium hydroxide in methanol
T=20°C; Aldol condensation; 24 h;
参考文献
Pedrini, Fernanda Spezia; Chiaradia, Louise Domeneghini; Licinio, Marley Aparecida; De Moraes, Ana Carolina Rabello; Curta, Juliana Costa; Costa, Aline; Mascarello, Alessandra; Creczinsky-Pasa, Tania Beatriz; Nunes, Ricardo Jose; Yunes, Rosendo Augusto; Santos-Silva, Maria Claudia
Journal of Pharmacy and Pharmacology, 2010 , vol. 62, # 9 p. 1128 - 1136
