3-羟基-4-甲氧基苯乙酸合成路线 （共 40 条）
反应条件
sodium hydroxide 1.) 50 deg C, 48 h, 2.) 100 deg C;
参考文献
Szantay; Dornyei; Blasko; et al.
Archiv der Pharmazie, 1981 , vol. 314, # 12 p. 983 - 991
反应条件
iron(II) sulfate in ammonium hydroxide; ammonia; water T=80 - 90°C; 1 h;
参考文献
Majumder; Sarkar
Journal of the Indian Chemical Society, 1989 , vol. 66, # 8-10 p. 673 - 680
反应条件
sodium hydroxide; copper(II) sulfate in water T=110°C; 216 h; sealed tube; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 49, # 11 p. 2061 - 2063
反应条件
hydrogenchloride; zinc in water; acetic acid T=5°C; 5 h;
参考文献
Majumder; Sarkar
Journal of the Indian Chemical Society, 1989 , vol. 66, # 8-10 p. 673 - 680
反应条件
1: 82 percent / 2 N aq. NaOH / 6 h / 50 °C 2: 68 percent / 99percent formic acid / 10percent Pd-C / 6 h / 100 °C View Scheme
参考文献
Archiv der Pharmazie, , vol. 314, # 12 p. 983 - 991
反应条件
1: 91 percent / 2 N aq. NaOH 2: 76 percent / 99percent formic acid / 10percent Pd-C / 3 h / 100 °C View Scheme
参考文献
Archiv der Pharmazie, , vol. 314, # 12 p. 983 - 991
反应条件
1: acetic acid; bromine / 2 h / 20 °C 2: potassium carbonate / acetone / |Reflux 3: potassium hydroxide; water; copper; copper(II) oxide / 1 h / 140 °C / |Inert atmosphere; |Microwave irradiation View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 21, # 4 p. 856 - 868
反应条件
1: potassium carbonate / acetone / |Reflux 2: potassium hydroxide; water; copper; copper(II) oxide / 1 h / 140 °C / |Inert atmosphere; |Microwave irradiation View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 21, # 4 p. 856 - 868
反应条件
sulfuric acid; sodium nitrite Eintragen der Reaktionsloesung in heisse wss. Schwefelsaeure;
参考文献
Journal of Organic Chemistry, , vol. 5, p. 606,608
反应条件
1: ethanolic KOH-solution 2: acetic acid; nitric acid / <0 3: palladium; methanol / Hydrogenation 4: aqueous sulfuric acid; sodium nitrite / Eintragen der Reaktionsloesung in heisse wss. Schwefelsaeure View Scheme
参考文献
Journal of Organic Chemistry, , vol. 5, p. 606,608
