4-(3-溴丙基)苯甲酸甲酯合成路线 （共 8 条）
反应条件
carbon tetrabromide; triphenylphosphine in dichloromethane 1.) 0 deg C, 30 min, 2.) RT, overnight;
参考文献
Varney, Michael D.; Palmer, Cindy L.; Romines III, William H.; Boritzki, Theodore; Margosiak, Stephen A.; Almassy, Robert; Janson, Cheryl A.; Bartlett, Charlotte; Howland, Eleanor J.; Ferre, Rosanne
Journal of Medicinal Chemistry, 1997 , vol. 40, # 16 p. 2502 - 2524
反应条件
1: H2 / Pd/C 2: CDI; allyl bromide View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 7 p. 1799 - 1802
反应条件
1: 95 percent / H2 / 5percent Pd-C / ethanol / 3.5 h / 2327.2 Torr 2: 95 percent / CBr4, Ph3P / CH2Cl2 / 1.) 0 deg C, 30 min, 2.) RT, overnight View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 16 p. 2502 - 2524
参考文献
US2002/65308 A1, ;
US 20020065308 A1
反应条件
1: 88 percent / CS2 / 5 °C 2: 68 percent / Br2, NaOH / 2 h / 5 °C 3: 97 percent / 5 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 4 p. 523 - 528
参考文献
Schmid, Christopher R.; Sluka, James P.; Duke, Kristen M.; Glasebrook, Andrew W.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 4 p. 523 - 528
反应条件
allyl bromide; 1,1'-carbonyldiimidazole
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 7 p. 1799 - 1802
反应条件
1: 68 percent / Br2, NaOH / 2 h / 5 °C 2: 97 percent / 5 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 4 p. 523 - 528
