5-甲氧基-3-吡啶甲醛合成路线 （共 11 条）
反应条件
1: 3-Bromo-5-methoxypyridine With isopropylmagnesium chloride in tetrahydrofuran 2: N,N-dimethyl-formamide in tetrahydrofuran
参考文献
Ikemoto, Norihiro; Miller, Ross A.; Fleitz, Fred J.; Liu, Jinchu; Petrillo, Daniel E.; Leone, Joseph F.; Laquidara, Joseph; Marcune, Benjamin; Karady, Sandor; Armstrong III, Joseph D.; Volante, Ralph P.
Tetrahedron Letters, 2005 , vol. 46, # 11 p. 1867 - 1871
反应条件
pyridine; chromium(VI) oxide Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 3 p. 583 - 593
反应条件
n-butyllithium in tetrahydrofuran; ethyl acetate; N,N-dimethyl-formamide
参考文献
Cytovia, Inc.
Patent: US2003/65018 A1, 2003 ;
反应条件
1: methanol / 72 h / Heating 2: n-BuLi / -78 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 21 p. 4745 - 4751
反应条件
sulfur in decalin 6 h; Heating;
参考文献
Comins, Daniel L.; Herrick, James J.
Heterocycles, 1987 , vol. 26, # 8 p. 2159 - 2164
反应条件
1: LiAlH4 / diethyl ether / Heating 2: CrO3, pyridine / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 3 p. 583 - 593
反应条件
1: 50 percent / NaBH4 / methanol / -78 °C 2: 1.) POCl3, 2.) KOAc / 1.) CH2Cl2, RT, 24 h, 2.) CH2Cl2, water, reflux, 20 min 3: 69 percent / sulfur / decahydronaphthalene / 6 h / Heating View Scheme
参考文献
Heterocycles, , vol. 26, # 8 p. 2159 - 2164
反应条件
1: 1.) POCl3, 2.) KOAc / 1.) CH2Cl2, RT, 24 h, 2.) CH2Cl2, water, reflux, 20 min 2: 69 percent / sulfur / decahydronaphthalene / 6 h / Heating View Scheme
参考文献
Heterocycles, , vol. 26, # 8 p. 2159 - 2164
反应条件
1: With hydroxylamine hydrochloride in methanol T=25°C; 4 h; 2: With pyridine; methanesulfonyl chloride T=25°C; 2 h;
参考文献
French, Jarrod B.; Cen, Yana; Vrablik, Tracy L.; Xu, Ping; Allen, Eleanor; Hanna-Rose, Wendy; Sauve, Anthony A.
Biochemistry, 2010 , vol. 49, # 49 p. 10421 - 10439
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Comins, Daniel L.; Killpack, Michael O.
Journal of Organic Chemistry, 1990 , vol. 55, # 1 p. 69 - 73
