3-(4-羟基哌啶-1-基)-3-甲基吡咯烷-1-羧酸乙酯合成路线 （共 2 条）
反应条件
1: in tetrahydrofuran; toluene T=0 - 20°C; 12 h; 2: With water; ammonium chloride in tetrahydrofuran; toluene T=0°C;
参考文献
ASTRAZENECA AB
Patent: US2009/221567 A1, 2009 ;
Location in patent: Page/Page column 59 ;
US 20090221567 A1
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide in dichloromethane T=-78°C; Swern Oxidation; 0.333333 h; 2: With triethylamine in dichloromethane T=-78 - 20°C; 1 h;
参考文献
ASTRAZENECA AB
Patent: US2009/221567 A1, 2009 ;
Location in patent: Page/Page column 59; 60 ;
US 20090221567 A1
