(4-甲基-2-吡啶)溴化镁合成路线 (共 2 条)
反应条件
in tetrahydrofuran T=20°C;
参考文献
ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.
Patent: WO2004/14902 A2, 2004 ;
Location in patent: Page 41 ;
WO 2004/014902 A2
反应条件
C42H64O4P2Pd in tetrahydrofuran
T=60°C; Kumada-Corriu coupling reaction; 20 h; Inert atmosphere; chemoselective reaction;
参考文献
Ackermann, Lutz; Potukuchi, Harish K.; Kapdi, Anant R.; Schulzke, Carola
Chemistry - A European Journal, 2010 , vol. 16, # 11 p. 3300 - 3303