1: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 3 h, 2.) -78 deg C, 15 min 2: 1.) 50percent NaH in mineral oil / 1.) DMF, room temp., 1 h, 2.) DMF, room temp., 0.5 h 3: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 3 h, 2.) -78 deg C, 15 min View Scheme

1: 1.) 50percent NaH in mineral oil / 1.) DMF, room temp., 1 h, 2.) DMF, room temp., 0.5 h 2: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 3 h, 2.) -78 deg C, 15 min View Scheme

1: 1.) 50percent NaH in mineral oil / 1.) DMF, room temp., 1 h, 2.) DMF, room temp., 0.5 h 2: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 3 h, 2.) -78 deg C, 15 min View Scheme

n-butyllithium 1.) THF, hexane, 0 deg C, 3 h, 2.) -78 deg C, 15 min; Yield given. Multistep reaction. Yields of byproduct given;