trifluoroacetic anhydride in dichloromethane 168 h; Ambient temperature;

1: 1 h; Reflux; 2: With hydrogenchloride; water 0.5 h; Reflux;

1: 1) NaNO2, conc. HCl, 2) hexafluorophosphoric acid / 1) H2O, -5 to 0 deg C, 5 min 2: m-chloroperbenzoic acid / CH2Cl2 / 16 h / Ambient temperature 3: 72 percent / HNO3, 30percent oleum, conc. H2SO4 / 1) 5 deg C to RT, 1 h, 2) steam bath, 2 h 4: 89 percent / POCl3 / CH2Cl2 / 1) RT, 16 h, 2) reflux, 4 h 5: 53 percent / trifluoroacetic anhydride / CH2Cl2 / 168 h / Ambient temperature View Scheme

1: m-chloroperbenzoic acid / CH2Cl2 / 16 h / Ambient temperature 2: 72 percent / HNO3, 30percent oleum, conc. H2SO4 / 1) 5 deg C to RT, 1 h, 2) steam bath, 2 h 3: 89 percent / POCl3 / CH2Cl2 / 1) RT, 16 h, 2) reflux, 4 h 4: 53 percent / trifluoroacetic anhydride / CH2Cl2 / 168 h / Ambient temperature View Scheme

1: 72 percent / HNO3, 30percent oleum, conc. H2SO4 / 1) 5 deg C to RT, 1 h, 2) steam bath, 2 h 2: 89 percent / POCl3 / CH2Cl2 / 1) RT, 16 h, 2) reflux, 4 h 3: 53 percent / trifluoroacetic anhydride / CH2Cl2 / 168 h / Ambient temperature View Scheme

1: 89 percent / POCl3 / CH2Cl2 / 1) RT, 16 h, 2) reflux, 4 h 2: 53 percent / trifluoroacetic anhydride / CH2Cl2 / 168 h / Ambient temperature View Scheme

1 h; Reflux;

manganese(IV) oxide in dichloromethane