phosphorus tribromide in toluene T=100°C; 1 h;

1: 40 percent / B2H6 / tetrahydrofuran / 1.5 h 2: 61 percent / PBr3 / toluene / 1 h / 100 °C View Scheme

1: 90 percent / NaOEt / ethanol / 2 h / Heating 2: 2M NaOH / methanol; H2O / 3 h / 40 °C 3: 92 percent / p-xylene / 2 h / Heating 4: Aspergillus genus acylase; 0.2 M AcONa; 0.2 M NaOH / H2O / 48 h / 38 °C / pH 8.0 View Scheme

tetrabutyl ammonium fluoride in tetrahydrofuran Hass-Bender/Henry reaction;

1: With thiourea in ethanol 2.5 h; Heating / reflux; 2: With sodium hydroxide; water in water T=20°C; Heating / reflux; 3: With hydrogenchloride; water in water T=0°C; pH=6;

1: in ethanol 3 h; Heating / reflux; 2: With sodium hydroxide in ethanol; water 3 h; Heating / reflux;