反应条件
1: HCl / acetic acid / 2 h / 100 °C
2: 69 percent / DBU / acetonitrile / 1.) reflux, 2.5 h, 2.) room temperature, overnight
View Scheme
参考文献
Domagala, John M.; Heifetz, Carl L.; Hutt, Marland P.; Mich, Thomas F.; Nichols, Jeffry B.; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 991 - 1001
