2,6-二氯吡啶-4-甲醛合成路线 （共 10 条）
反应条件
1: 2,6-Dichloropyridine With N-tetramethylpiperidine magnesium chloride; lithium chloride in tetrahydrofuran T=25°C; 0.1 h; 2: N,N-dimethyl-formamide in tetrahydrofuran T=-30°C;
参考文献
Krasovskiy, Arkady; Krasovskaya, Valeria; Knochel, Paul
Angewandte Chemie - International Edition, 2006 , vol. 45, # 18 p. 2958 - 2961
参考文献
Osuka, Atsuhiro; Yoneshima, Ryusho; Shiratori, Hideo; Okada, Tadashi; Taniguchi, Seiji; Mataga, Noboru
Chemical Communications, 1998 , # 15 p. 1567 - 1568
反应条件
in tetrahydrofuran T=-20°C;
参考文献
EP1810974 A1, ;
Page/Page column 4; 7-8 ;
反应条件
1: 78 percent / POCl3 / 160 °C 2: 74 percent / NaBH4, BF3*Et2O 3: 66 percent / MnO2 View Scheme
参考文献
Chemical Communications, , # 15 p. 1567 - 1568
反应条件
1: 74 percent / NaBH4, BF3*Et2O 2: 66 percent / MnO2 View Scheme
参考文献
Chemical Communications, , # 15 p. 1567 - 1568
反应条件
Pd-BaSO4; xylene T=160 - 170°C; Hydrogenation;
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2>134, p. 177,184
反应条件
1: sodium tris(acetoxy)borohydride / ethanol / 3 h / 80 °C 2: Dess-Martin periodane / dichloromethane / 0.5 h / 20 °C View Scheme
反应条件
n-butyllithium 1) THF, -80 deg C, 30 min, 2) 30 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 56, # 15 p. 4793 - 4796
参考文献
Graf
Journal fuer Praktische Chemie (Leipzig), 1932 , vol. <2>134, p. 177,184
反应条件
diethylamino-sulfur trifluoride in dichloromethane T=-78 - 20°C; Inert atmosphere;
参考文献
NOVARTIS AG
Patent: WO2009/150230 A1, 2009 ;
Location in patent: Page/Page column 79 ;
WO 2009/150230 A1
