N-[6-(4,4,5,5-四甲基-1,3,2-二氧硼杂环戊烷-2-基)萘-2-基]甲烷磺酰胺合成路线 （共 3 条）
反应条件
potassium acetate; Combiphos Pd6 in toluene 3 h; Heating / reflux;
参考文献
ABBOTT LABORATORIES; ROCKWAY, Todd W.; BETEBENNER, David A.; DEGOEY, David A.; FLENTGE, Charles A.; HUTCHINSON, Douglas K.; KATI, Warren M.; KRUEGER, Allan C.; LIU, Dachun; LONGENECKER, Kenton L.; PRATT, John K.; STEWART, Kent D.; WAGNER, Rolf
Patent: WO2010/111437 A1, 2010 ;
Location in patent: Page/Page column 74 ;
WO 2010/111437 A1
反应条件
sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in ethanol; water; toluene
T=100°C; Suzuki Coupling; 1.33333 h; Microwave irradiation; Product distribution / selectivity;
参考文献
ABBOTT LABORATORIES
Patent: WO2009/39134 A1, 2009 ;
Location in patent: Page/Page column 109 ;
反应条件
sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in ethanol; water; toluene
T=100°C; Suzuki Coupling; 1 h; Microwave irradiation; Product distribution / selectivity;
参考文献
ABBOTT LABORATORIES
Patent: WO2009/39127 A1, 2009 ;
Location in patent: Page/Page column 180 ;
