1: With urea hydrogen peroxide addition compound; sodium hydroxide in ethanol; water T=20°C; Ice cooling bath; 2: With hydrogenchloride in water; ethyl acetate pH=4;
参考文献
PFIZER INC.; MASCITTI, Vincent; MCCLURE, Kim Francis; MUNCHHOF, Michael John; ROBINSON, Ralph Pelton, Jr.
Patent: WO2012/69948 A1, 2012 ;
Location in patent: Page/Page column 64 ;