1: N,N-dimethyl-formamide With POCl3 T=5 - 20°C; Vilsmeier formylation; 0.583333 h; 2: 4-methoxy-2,3-methylenedioxyphenol T=20 - 75°C; Vilsmeier formylation;

boron trichloride in dichloromethane 0.25 h; Ambient temperature;

1: 87 percent / POCl3 / 48 h / Ambient temperature 2: 70 percent / BCl3 / CH2Cl2 / 0.25 h / Ambient temperature View Scheme

1: 80 percent / BCl3 / CH2Cl2 / 5 h / Ambient temperature 2: 52 percent / CsF / dimethylformamide / 6 h / 120 °C 3: 87 percent / POCl3 / 48 h / Ambient temperature 4: 70 percent / BCl3 / CH2Cl2 / 0.25 h / Ambient temperature View Scheme

1: K2CO3 / acetone / 17 h / Heating 2: 80 percent / BCl3 / CH2Cl2 / 5 h / Ambient temperature 3: 52 percent / CsF / dimethylformamide / 6 h / 120 °C 4: 87 percent / POCl3 / 48 h / Ambient temperature 5: 70 percent / BCl3 / CH2Cl2 / 0.25 h / Ambient temperature View Scheme

1: 52 percent / CsF / dimethylformamide / 6 h / 120 °C 2: 87 percent / POCl3 / 48 h / Ambient temperature 3: 70 percent / BCl3 / CH2Cl2 / 0.25 h / Ambient temperature View Scheme

1: 21.8 g / 85percent m-chloroperoxybenzoic acid / CH2Cl2 / 5 h 2: K2CO3 / acetone / 17 h / Heating 3: 80 percent / BCl3 / CH2Cl2 / 5 h / Ambient temperature 4: 52 percent / CsF / dimethylformamide / 6 h / 120 °C 5: 87 percent / POCl3 / 48 h / Ambient temperature 6: 70 percent / BCl3 / CH2Cl2 / 0.25 h / Ambient temperature View Scheme