2-乙基-5-甲基-1,3-恶唑-4-羧酸合成路线 (共 3 条)
反应条件
potassium hydroxide in ethanol 48 h; Ambient temperature;
参考文献
Cornwall, Philip; Dell, Colin P.; Knight, David W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 10 p. 2417 - 2428
反应条件
1: 57 percent / SOCl2 / benzene / 1.) 30 deg C, 10 min, 2.) water-pump vacuum, 0.5 h 2: 68 percent / KOH / ethanol / 48 h / Ambient temperature View Scheme
参考文献
Cornwall, Philip; Dell, Colin P.; Knight, David W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 10 p. 2417 - 2428
反应条件
n-butyllithium 1.) -78 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Cornwall, Philip; Dell, Colin P.; Knight, David W.
Tetrahedron Letters, 1987 , vol. 28, # 31 p. 3585 - 3588