1: 95 percent / dimethylaminopyridine, pyridine / 6 h / 25 °C 2: 1.) zinc dust, Ph3P 2.) pyridine / 1.) CH2Cl2, 15 min, r.t. 2.) CH2Cl2, 30 min r.t. 3: n-butyllithium / tetrahydrofuran; hexane / -78 to 20 deg C 5: 91 percent / Et3N / bis-triphenylphosphine palladium dichloride / dimethylformamide / 1.5 h / 75 °C 6: 95 percent / H2 / Lindlar's catalyst, quinoline / hexane / 0.75 h 7: 2.) AG 50W-X4 resin / 1.) iso-octane, 4 h, reflux 2.) methanol, CH2Cl2, 24 h, r.t. 8: 80 percent / diethyl ether / 0.33 h / -78 °C View Scheme