2,3,4,5-四氯-6-(三氯甲基)吡啶合成路线 （共 15 条）
反应条件
sulfuric acid; hydrazine; water; triethylamine 1.) C2H5OH, reflux, 1 h; Multistep reaction. Title compound not separated from byproducts;
参考文献
Sipyagin, A. M.; Aliev, Z. G.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1993 , vol. 29, # 11 p. 1287 - 1290
Khimiya Geterotsiklicheskikh Soedinenii, 1993 , # 11 p. 1495 - 1498
反应条件
1: 78.86 percent / NaOH / 2 h / Heating 2: 52.26 percent / DMSO / 0.75 h / 150 °C View Scheme
参考文献
Tiwari, Anita; Riordan, James M.; Waud, William R.; Struck, Robert F.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 5 p. 1079 - 1085
反应条件
chlorine T=200°C; Rate constant;
参考文献
Emel'yanov, V. I.; Stul', B. Ya.; Korolev, B. M.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, # 6 p. 1168 - 1171
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 6 p. 1308 - 1312
反应条件
ammonia T=100°C; 1 h;
参考文献
Ovchinnikov, V.G.; Nasyr, I.A.; Litvinenko, G.S.; Maksimeno, N.M.; Zatsarevnyi, V.M.
J. Appl. Chem. USSR (Engl. Transl.), 1991 , vol. 64, # 12 p. 2490 - 2497,2327 - 2334
反应条件
ammonia in dimethyl sulfoxide
T=100°C; 0.5 h;
参考文献
Ovchinnikov, V.G.; Nasyr, I.A.; Litvinenko, G.S.; Maksimeno, N.M.; Zatsarevnyi, V.M.
J. Appl. Chem. USSR (Engl. Transl.), 1991 , vol. 64, # 12 p. 2490 - 2497,2327 - 2334
