4,4'-二甲基-2,2'-联吡啶合成路线 （共 79 条）
反应条件
selenium(IV) oxide; sulfuric acid
参考文献
Kikkeri, Raghavendra; Liu, Xinyu; Adibekian, Alexander; Tsai, Yu-Hsuan; Seeberger, Peter H.
Chemical Communications, 2010 , vol. 46, # 13 p. 2197 - 2199
反应条件
potassium permanganate; sulfuric acid 12 h; Heating;
参考文献
Australian Journal of Chemistry, , vol. 39, # 7 p. 1053 - 1062
反应条件
selenium(IV) oxide in 1,4-dioxane 72 h;
参考文献
Eckermann, Amanda L.; Barker, Kylie D.; Hartings, Matthew R.; Ratner, Mark A.; Meade, Thomas J.
Journal of the American Chemical Society, 2005 , vol. 127, # 34 p. 11880 - 11881
反应条件
chloro-trimethyl-silane; 1,1,2,2-tetrachloro-1,2-difluoroethane; caesium carbonate; cesium fluoride; lithium diisopropyl amide 1.) THF, -78 deg C, 2.) DMF, 25 deg C; Yield givenMultistep reaction;
参考文献
Tetrahedron Letters, , vol. 40, # 18 p. 3647 - 3650
反应条件
n-butyllithium; diisopropylamine in tetrahydrofuran T=0 - 20°C; 15 h; Inert atmosphere;
参考文献
Neuthe, Katja; Bittner, Florian; Stiemke, Frank; Ziem, Benjamin; Du, Juan; Zellner, Monika; Wark, Michael; Schubert, Thomas; Haag, Rainer
Dyes and Pigments, 2014 , vol. 104, p. 24 - 33
反应条件
1: 4,4'-dimethyl-2,2'-bipyridine With n-butyllithium; diisopropylamine in tetrahydrofuran T=0°C; 1 h; 2: allyl bromide in tetrahydrofuran T=0 - 20°C;
参考文献
TPI ENTERPRISES PTY LTD
Patent: WO2009/152577 A1, 2009 ;
Location in patent: Page/Page column 15-16 ;
反应条件
1: 4,4'-dimethyl-2,2'-bipyridine With lithium diisopropyl amide in tetrahydrofuran T=-40 - -5°C; 1 h; 2: 1-bromo-butane in tetrahydrofuran T=-20 - 0°C; 2 h; Further stages.;
参考文献
Bernhard, Stefan; Barron, Jason A.; Houston, Paul L.; Abruna, Hector D.; Ruglovksy, Jennifer L.; Gao, Xicun; Malliaras, George G.
Journal of the American Chemical Society, 2002 , vol. 124, # 45 p. 13624 - 13628
反应条件
1: dihydrogen peroxide / water; acetic acid / 8 h / 100 °C 2: benzoyl chloride / dichloromethane / 72 h / 20 °C / Reflux View Scheme
参考文献
Lewis, Frank W.; Harwood, Laurence M.; Hudson, Michael J.; Distler, Petr; John, Jan; Stamberg, Karel; Nunez, Ana; Galan, Hitos; Espartero, Amparo G.
European Journal of Organic Chemistry, 2012 , # 8 p. 1509 - 1519
反应条件
sulfuric acid; hydrogen bromide 6 h; Reflux;
参考文献
Li, Yinan; Liu, Yifan; Nam, Dayoung; Park, Sungnam; Yoon, Juyoung; Hyun, Myung Ho
Dyes and Pigments, 2014 , vol. 100, # 1 p. 241 - 246
反应条件
1: 4,4'-dimethyl-2,2'-bipyridine With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 1 h; 2: 1,6-dibromo-n-hexane in tetrahydrofuran T=0°C; 1.5 h;
参考文献
Petitjean, Anne; Barton, Jacqueline K.
Journal of the American Chemical Society, 2004 , vol. 126, # 45 p. 14728 - 14729
