1-苄基-4-(2-甲氧基苯基)四氢吡啶合成路线 （共 7 条）
反应条件
methanesulfonic acid in toluene 4 h; Reflux;
参考文献
Conway, Richard J.; Valant, Celine; Christopoulos, Arthur; Robertson, Alan D.; Capuano, Ben; Crosby, Ian T.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 7 p. 2560 - 2564
反应条件
tetrabutyl ammonium fluoride; tris(dibenzylideneacetone)dipalladium(0) chloroform complex in tetrahydrofuran T=50°C;
参考文献
Morrill, Christie; Mani, Neelakandha S.
Organic Letters, 2007 , vol. 9, # 8 p. 1505 - 1508
反应条件
toluene-4-sulfonic acid; trifluoroacetic acid in toluene 5 h; Heating;
参考文献
Jaen, Juan C.; Wise, Lawrence D.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1317 - 1319
反应条件
1.1: n-BuLi / hexane; tetrahydrofuran / -70 - 1 °C 1.2: 23.1 percent / tetrahydrofuran / 20 °C 2.1: 15.6 percent / p-toluenesulfonic acid monohydrate / toluene / 18 h / Heating View Scheme
参考文献
Conway, Richard J.; Valant, Celine; Christopoulos, Arthur; Robertson, Alan D.; Capuano, Ben; Crosby, Ian T.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 7 p. 2560 - 2564
反应条件
1.1: n-BuLi / hexane; tetrahydrofuran / -70 - 1 °C 1.2: 23.1 percent / tetrahydrofuran / 20 °C 2.1: 15.6 percent / p-toluenesulfonic acid monohydrate / toluene / 18 h / Heating View Scheme
参考文献
Conway, Richard J.; Valant, Celine; Christopoulos, Arthur; Robertson, Alan D.; Capuano, Ben; Crosby, Ian T.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 7 p. 2560 - 2564
反应条件
in tetrahydrofuran 1 h; Heating;
参考文献
Komoto, Teruo; Hirota, Hiroyuki; Otsuka, Mari; Kotake, Jiro; Hasegawa, Susumu; Koya, Hidehiko; Sato, Susumu; Sakamoto, Takao
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 12 p. 1978 - 1985
反应条件
palladium monocarbide in ethanol
参考文献
SSP Co., Ltd.
Patent: EP1325912 A1, 2003 ;
EP 1325912 A1
