4-(1-羟基乙基)苯磺酰胺合成路线 （共 2 条）
反应条件
1: 87 percent / pyridine / 2 h / -10 °C 2: 1.) 1,8-diazabicyclo<5.4.0>undec-7-ene / 1.) benzene, RT, 30 min, 2.) benzene, RT, 1 h 3: 90 percent / K2CO3, MeOH / 12 h / Ambient temperature View Scheme
参考文献
Akita, Hiroyuki; Kurashima, Katsumi; Nozawa, Masako; Yamamura, Shigeo; Seri, Kenzi; Imamura, Yorishige
Tetrahedron Asymmetry, 1998 , vol. 9, # 24 p. 4331 - 4340
反应条件
Multi-step reaction with 2 steps 1.1: 47 percent / CuI / dimethylsulfoxide / 110 °C2.1: NaOMe / dimethylsulfoxide; methanol / 0.25 h / 20 °C2.2: 50 percent / NH2OSO3H; NaOAc / H2O / 16 h / 20 °C
参考文献
Baskin, Jeremy M; Wang, Zhaoyin Tetrahedron Letters, 2002 , vol. 43, # 47 p. 8479 - 8483
