1: 95 percent / 10percent aq. HCl / acetone / 6 h 2: 1.) Mg / 1.) THF, 2.) THF, RT, 3 h 3: pyridine / 20 h / 0 °C 4: NaI, Zn / tetrahydrofuran / 3 h / Heating 5: 95 percent / 10percent aq. HCl / acetone / 6 h / 40 °C 6: 95 percent / diisobutylaluminium hydride / diethyl ether; toluene / 1.5 h / -10 °C 7: 75 percent / pyridine View Scheme

Multi-step reaction with 2 steps 1: 95 percent / aq. HCl / acetone / 6 h2: 1.) Mg / 1) THF; 2) THF, room temperature  

Multi-step reaction with 3 steps 1: 95 percent / aq. HCl / acetone / 6 h2: 1.) Mg / 1) THF; 2) THF, room temperature3: 10.9 g / pyridine / 20 h / 0 °C