四氢双脱甲氧基二阿魏酰甲烷合成路线 （共 7 条）
反应条件
1: With lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 0.583333 h;
2: With potassium carbonate in methanol
0.5 h;
参考文献
Kim, Darrick S. H. L.
Patent: US6887898 B1, 2005 ;
Location in patent: Page/Page column 19; sheet 2 ;
反应条件
H2; nickel in tetrahydrofuran; methanol; chloroform
参考文献
WARNER-LAMBERT COMPANY
Patent: EP245825 B1, 1991 ;
反应条件
formic acid; triethylamine; 5 wt palladium on calcium carbonate in ethyl acetate
9 h; Heating / reflux;
参考文献
GOKARAJU, Ganga, Raju; GOKARAJU, Rama, Raju; GOTTUMUKKALA, Venkata, Subbaraju; SOMEPALLI, Venkateswarlu
Patent: WO2007/43058 A1, 2007 ;
Location in patent: Page/Page column 15 ;
反应条件
1: n-butylamine; tri-n-butylborate
2: HCl
3: 65 percent / H2 / Pd/C / ethyl acetate; methanol / 2 h / 20 °C
View Scheme
参考文献
Portes, Elise; Gardrat, Christian; Castellan, Alain
Tetrahedron, 2007 , vol. 63, # 37 p. 9092 - 9099
反应条件
1: boric anhydride
2: n-butylamine; tri-n-butylborate
3: HCl
4: 65 percent / H2 / Pd/C / ethyl acetate; methanol / 2 h / 20 °C
View Scheme
参考文献
Portes, Elise; Gardrat, Christian; Castellan, Alain
Tetrahedron, 2007 , vol. 63, # 37 p. 9092 - 9099
反应条件
10 palladium on activated charcoal
参考文献
Tocharus, Jiraporn; Jamsuwan, Sataporn; Tocharus, Chainarong; Changtam, Chatchawan; Suksamrarn, Apichart
Journal of Natural Medicines, 2012 , vol. 66, # 2 p. 400 - 405
反应条件
sodium tetrahydroborate in methanol
参考文献
Changtam, Chatchawan; de Koning, Harry P.; Ibrahim, Hasan; Sajid, M. Sohail; Gould, Matthew K.; Suksamrarn, Apichart
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 3 p. 941 - 956
