3-(3-羟基-4-甲氧基苯基)-丙酸合成路线 (共 12 条)
反应条件
1: K2CO3 / acetone; acetonitrile / 25 h / Heating
2: 1.02 g / KOH / methanol; H2O / 10 h / 70 °C
3: oxalyl chloride / CH2Cl2 / 20 h / 20 °C
4: tetrahydrofuran; hexane; acetonitrile / 4 h
View Scheme
参考文献
Li, Dajie; Zhao, Baoping; Sim, Sai-Peng; Li, Tsai-Kun; Liu, Angela; Liu, Leroy F.; LaVoie, Edmond J.
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 17 p. 3795 - 3805
反应条件
1: hydrogen chloride
2: potassium carbonate; methanol
View Scheme
参考文献
Robinson; Sugasawa
Journal of the Chemical Society, 1931 , p. 3163,3168
Journal of the Chemical Society, 1933 , p. 280