3-(4-甲氧基苯基)-3-甲基丁酸合成路线 （共 9 条）
反应条件
1: With AlCl3, aluminium chloride
T=20 - 35°C; 4 h;
2: With water
T=0°C; 1.33333 h;
3: With hydrogen bromide in water
参考文献
Boehringer Ingelheim Pharma GmbH and Co. KG
Patent: US2006/173196 A1, 2006 ;
Location in patent: Page/Page column 4 ;
反应条件
aluminium trichloride
参考文献
Winstein,S.; Heck,R.F.
Journal of Organic Chemistry, 1972 , vol. 37, p. 825 - 836
反应条件
sodium methylate
Erwaermen des Reaktionsprodukts mit wss.-aethanol. KOH;
参考文献
Heck et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 3278,3283
反应条件
sulfuric acid
Behandeln des Reaktionsprodukts mit Magnesium in Aether und anschliessend mit CO2;
参考文献
Heck et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 3278,3283
反应条件
1: AlCl3; CS2
2: aqueous NaOH
View Scheme
参考文献
Goo-on et al.
Journal of Organic Chemistry, 1954 , vol. 19, p. 305,309
反应条件
1: AlCl3; CS2
2: aqueous NaOH
View Scheme
参考文献
Goo-on et al.
Journal of Organic Chemistry, 1954 , vol. 19, p. 305,309
反应条件
1: (i) CuI, (ii) aq. HCl
2: aq. KOH
View Scheme
参考文献
Kundu,A.K. et al.
Journal of the Chemical Society, 1965 , p. 2749 - 2763
反应条件
1: NH4OAc
2: (i) CuI, (ii) aq. HCl
3: aq. KOH
View Scheme
参考文献
Kundu,A.K. et al.
Journal of the Chemical Society, 1965 , p. 2749 - 2763
参考文献
Boehringer Ingelheim Pharma GmbH and Co. KG
Patent: US2006/173196 A1, 2006 ;
Location in patent: Page/Page column 4-5 ;
