4-氯-1-(四氢-2H-吡喃-2-基)-1H-吲唑合成路线

参考文献

Genentech, Inc.; Heald, Robert Andrew; McLean, Neville James
Patent: US2014/65136 A1, 2014 ;
Location in patent: Paragraph 0189 ;

110-87-23,4-二氢-2H-吡喃+

13096-96-34-氯-1H-吲唑

1137278-45-54-氯-1-(四氢-2H-吡喃-2-基)-1H-吲唑+

1146955-34-1

参考文献

Tian, Qingping; Cheng, Zhigang; Yajima, Herbert M.; Savage, Scott J.; Green, Keena L.; Humphries, Theresa; Reynolds, Mark E.; Babu, Srinivasan; Gosselin, Francis; Askin, David; Kurimoto, Isao; Hirata, Norihiko; Iwasaki, Mitsuhiro; Shimasaki, Yasuharu; Miki, Takashi
Organic Process Research and Development, 2013 , vol. 17, # 1 p. 97 - 107

87-60-53-氯-2-甲基苯胺

1137278-45-54-氯-1-(四氢-2H-吡喃-2-基)-1H-吲唑

参考文献

Genentech, Inc.; Heald, Robert Andrew; McLean, Neville James
Patent: US2014/65136 A1, 2014 ;

1137278-45-54-氯-1-(四氢-2H-吡喃-2-基)-1H-吲唑+

1146955-34-1+

73183-34-3联硼酸频那醇酯

956388-05-91-(四氢-2H-吡喃-2-基)-4-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-1H-吲唑+

1146955-35-22-(四氢-2H-吡喃-2-基)-4-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-2H-吲唑

参考文献

GENENTECH, INC.; SUMITOMO CHEMICAL COMPANY, LIMITED
Patent: US2012/123122 A1, 2012 ;
Location in patent: Page/Page column 12 ;

1137278-45-54-氯-1-(四氢-2H-吡喃-2-基)-1H-吲唑+

73183-34-3联硼酸频那醇酯

956388-05-91-(四氢-2H-吡喃-2-基)-4-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-1H-吲唑

参考文献

GENENTECH, INC.; F. HOFFMANN-LA ROCHE AG
Patent: WO2009/146406 A1, 2009 ;
Location in patent: Page/Page column 66-67 ;
WO 2009/146406 A1

1137278-45-54-氯-1-(四氢-2H-吡喃-2-基)-1H-吲唑+

1146955-34-1+

73183-34-3联硼酸频那醇酯

956388-05-91-(四氢-2H-吡喃-2-基)-4-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-1H-吲唑+

1146955-35-22-(四氢-2H-吡喃-2-基)-4-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-2H-吲唑

参考文献

GENENTECH, INC.; SUMITOMO CHEMICAL COMPANY, LIMITED
Patent: US2012/123122 A1, 2012 ;
Location in patent: Page/Page column 12 ;