N-甲氧基-N-甲基异丁酰胺合成路线 （共 4 条）
反应条件
triethylamine in dichloromethane T=0 - 20°C; 1 h;
参考文献
Kerr, William J.; Morrison, Angus J.; Pazicky, Marek; Weber, Tina
Organic Letters, 2012 , vol. 14, # 9 p. 2250 - 2253
反应条件
pyridine in dichloromethane T=0 - 20°C; 3 h; Inert atmosphere;
参考文献
Trabbic, Christopher J.; Dietsch, Heather M.; Alexander, Evan M.; Nagy, Peter I.; Robinson, Michael W.; Overmeyer, Jean H.; Maltese, William A.; Erhardt, Paul W.
ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 1 p. 73 - 77
反应条件
1: (E)-4-methoxyacetophenone tosylhydrazone With Mes2Mg; lithium chloride in tetrahydrofuran T=40°C; Shapiro reaction; 3 h; 2: iPrCON(OMe)Me in tetrahydrofuran T=40°C; 0.5 h; 3: With water-d2 in tetrahydrofuran
参考文献
Kerr, William J.; Morrison, Angus J.; Pazicky, Marek; Weber, Tina
Organic Letters, 2012 , vol. 14, # 9 p. 2250 - 2253
反应条件
1: propargyladehyde di-ethyl acetal With n-butyllithium in tetrahydrofuran
T=-78 - -30°C;
2: iPrCON(OMe)Me in tetrahydrofuran
T=-78 - -30°C;
参考文献
Choung, Wonken; Lorsbach, Beth A.; Sparks, Thomas C.; Ruiz, James M.; Kurth, Mark J.
Synlett, 2008 , # 19 p. 3036 - 3040
