pig liver esterase; vinyl propionate; water; methoxypolyethylene glycol in toluene T=20°C; kinetic resolution; 408 h; Title compound not separated from byproducts;

4 A molecular sieve; N-ethyl-N,N-diisopropylamine; (S)-1-methyl-2-[(N-benzyl-N-methylamino)methyl]pyrrolidine in dichloromethane; N,N-dimethyl-formamide T=-78°C; 3 h; Title compound not separated from byproducts;