1,1-环己基二甲酸乙酯合成路线 （共 29 条）
反应条件
potassium hydroxide Hydrolysis;
参考文献
Fessenden,R.F. et al.
Journal of Medicinal Chemistry, 1964 , vol. 7, p. 695 - 698
反应条件
sodium in ethanol T=110 - 180°C; 3 h;
参考文献
Al-Ashmawi; Ghoneim; Khalifa
Pharmazie, 1980 , vol. 35, # 10 p. 591 - 593
反应条件
lithium tri-t-butoxyaluminum hydride in tetrahydrofuran
Heating / reflux;
参考文献
MEDIVIR UK Ltd; PEPTIMMUNE, Inc
Patent: WO2006/64286 A1, 2006 ;
Location in patent: Page/Page column 47-50 ;
WO 2006/064286 A1
反应条件
1: 89 percent / LiAlH4
4: LiAlH4
View Scheme
参考文献
Houk,J.; Whitesides,G.M.
Journal of the American Chemical Society, 1987 , vol. 109, p. 6825
反应条件
1: 89 percent / LiAlH4
View Scheme
参考文献
Houk,J.; Whitesides,G.M.
Journal of the American Chemical Society, 1987 , vol. 109, p. 6825
反应条件
sodium ethanolate
T=105°C; unter Druck;
参考文献
Dox; Yoder
Journal of the American Chemical Society, 1921 , vol. 43, p. 1368
反应条件
sodium ethanolate
T=105°C; unter Druck;
参考文献
Dox; Yoder
Journal of the American Chemical Society, 1921 , vol. 43, p. 1368
反应条件
T=105°C; im Autoklaven;
参考文献
Dox; Yoder
Journal of the American Chemical Society, 1921 , vol. 43, p. 1368
反应条件
sodium isopropanolate
参考文献
Cope; Kovacic; Burg
Journal of the American Chemical Society, 1949 , vol. 71, p. 3658,3659, 3662
