N,4-二甲基-N-(4-硝基苯基)-1-哌嗪乙酰胺合成路线 （共 3 条）
反应条件
potassium carbonate in acetone T=20°C; 3 h;
参考文献
Roth, Gerald J.; Heckel, Armin; Colbatzky, Florian; Handschuh, Sandra; Kley, Joerg; Lehmann-Lintz, Thorsten; Lotz, Ralf; Tontsch-Grunt, Ulrike; Walter, Rainer; Hilberg, Frank
Journal of Medicinal Chemistry, 2009 , vol. 52, # 14 p. 4466 - 4480
反应条件
in toluene T=40 - 55°C; 2.5 h; Product distribution / selectivity;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: WO2009/71523 A1, 2009 ;
Location in patent: Page/Page column 4; 23-24 ;
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; P=2585.81 Torr; 1.5 h;
参考文献
Journal of Medicinal Chemistry, , vol. 52, # 14 p. 4466 - 4480
