4-苄氧基-2-氟苯甲酸合成路线 （共 11 条）
反应条件
1: With water; potassium hydroxide in 1,4-dioxane
T=60°C; 5 h;
2: With sodium hydroxide in 1,4-dioxane; water
参考文献
MERCK and CO., INC.
Patent: WO2008/156721 A1, 2008 ;
Location in patent: Page/Page column 60 ;
参考文献
Jolidon, Synese; Rodriguez Sarmiento, Rosa Maria; Thomas, Andrew William; Wyler, Rene
Patent: US2003/236304 A1, 2003 ;
反应条件
hydrogenchloride; potassium hydroxide; sodium hydroxide; acetic acid in ethanol; water
参考文献
Chisso Corporation
Patent: US4784791 A1, 1988 ;
反应条件
1.1: K2CO3 / butan-2-one
2.1: n-BuLi / tetrahydrofuran
2.2: tetrahydrofuran
2.3: HOAc
View Scheme
参考文献
Hird, Michael; Goodby, John W.; Toyne, Kenneth J.; Gleeson, Helen F.; Peter Buxton; Seed, Alexander J.; Herbert, Mark R.
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2001 , vol. 365, p. 213 - 220
反应条件
1.1: K2CO3 / butan-2-one
2.1: n-BuLi / tetrahydrofuran
2.2: tetrahydrofuran
2.3: HOAc
View Scheme
参考文献
Hird, Michael; Goodby, John W.; Toyne, Kenneth J.; Gleeson, Helen F.; Peter Buxton; Seed, Alexander J.; Herbert, Mark R.
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2001 , vol. 365, p. 213 - 220
反应条件
1: potassium carbonate / butan-2-one
2: water
View Scheme
参考文献
Shubashree; Sadashiva; Dhara, Surajit
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2002 , vol. 381, p. 21 - 32
反应条件
1: potassium carbonate / butan-2-one
2: water
View Scheme
参考文献
Shubashree; Sadashiva; Dhara, Surajit
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2002 , vol. 381, p. 21 - 32
反应条件
1: Br2; AcOH
2: 96 percent / K2CO3 / butan-2-one
3: 71 percent / 1-methyl-pyrrolidin-2-one / 24 h / Heating
4: 58 percent / aq. NaOH / 60 h / Heating
View Scheme
参考文献
Cowling; Toyne; Goodby
Journal of Materials Chemistry, 2001 , vol. 11, # 6 p. 1590 - 1599
反应条件
1: 71 percent / 1-methyl-pyrrolidin-2-one / 24 h / Heating
2: 58 percent / aq. NaOH / 60 h / Heating
View Scheme
参考文献
Cowling; Toyne; Goodby
Journal of Materials Chemistry, 2001 , vol. 11, # 6 p. 1590 - 1599
反应条件
1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C
2: potassium hydroxide; water / 1,4-dioxane / 5 h / 60 °C
View Scheme
参考文献
MERCK and CO., INC.
Patent: WO2008/156721 A1, 2008 ;
