(S)-7-三氟甲基苯并二氢吡喃-4-胺合成路线 （共 3 条）
反应条件
palladium 10 on activated carbon; ammonia; hydrogen in methanol T=20°C; P=3102.97 Torr; 1 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 5 p. 1338 - 1341
反应条件
1: With Novozyme 435 (lipase acrylic resin from Candida antarctica) in tert-butyl methyl ether 3 h; Heating / reflux; 2: With hydrogenchloride in water 3: With sodium hydroxide in water pH=11; Purification / work up;
参考文献
US2009/93472 A1, ;
Page/Page column 14 ;
US 20090093472 A1
反应条件
1: pyridine / 24 h / 20 °C 2: palladium 10 on activated carbon; ammonia; hydrogen / methanol / 1 h / 20 °C / 3102.97 Torr View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 5 p. 1338 - 1341
