N(1),N(3)-二烯丙基胸腺嘧啶合成路线 (共 3 条)
反应条件
1: 5-methyl-2,4(1H,3H)-pyrimidinedione With sodium hydride; dimethyl sulfoxide T=20 - 60°C; 1 h; Inert atmosphere; 2: allyl bromide T=65°C; Inert atmosphereMicrowave irradiation;
参考文献
Sacarescu; Atudosie; Simionescu; Harabagiu
Chemistry of Heterocyclic Compounds, 2011 , vol. 47, # 5 p. 602 - 606
反应条件
in sodium hydroxide; acetone
参考文献
Tateoka; Kimura; Watanabe; Yamamoto; Ho
Chemical and pharmaceutical bulletin, 1987 , vol. 35, # 12 p. 4928 - 4934
反应条件
methyl-ethyl phosphite; palladium diacetate in acetonitrile 21 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Gundersen, Lise-Lotte; Benneche, Tore; Rise, Frode; Gogoll, Adolf; Undheim, Kjell
Acta Chemica Scandinavica, 1992 , vol. 46, # 8 p. 761 - 771