N-苄氧羰基-L-丙氨酸合成路线 (共 167 条)
反应条件
1: triethylamine; toluene; CHCl3 / anschliessend Behandeln mit L-Norvalin-aethylester-hydrochlorid 2: aqueous NaOH View Scheme
参考文献
Fu et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 6054,6057
反应条件
1: triethylamine, dicyclohexylcarbodiimide / CHCl3 2: 40percent HBr / acetic acid View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 60, p. 3081 - 3084
反应条件
hydrogen; K3[Co(CN)5] in methanol T=20°C; 3 h;
参考文献
Losse, Guenter; Stiehl, Hans-Ulrich
Zeitschrift fuer Chemie (Stuttgart, Germany), 1981 , vol. 21, # 5 p. 188
反应条件
1: N-methylmorpholine / CH2Cl2 / 0.33 h / -15 °C 2: N-methylmorpholine / CH2Cl2 / 1 h / -15 °C View Scheme
参考文献
Furukawa, M.; Hokama, N.; Okawara, T.
Synthesis, 1983 , # 1 p. 42 - 44
反应条件
dicyclohexyl-carbodiimide
参考文献
Voss,H.
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, Biochemie, Biophysik, Biologie, 1965 , vol. 20, p. 122 - 129
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1317 - 1324
反应条件
1.1: ClCOOEt; N-methylmorpholine / tetrahydrofuran / 0.25 h / -15 °C 1.2: tetrahydrofuran; CH2Cl2 / -15 - 20 °C 2.1: CF3COOAg / dioxane; H2O / 0.5 h / sonication View Scheme
参考文献
Drey, Charles N. C.; Mtetwa, Eli
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 7 p. 1587 - 1592
反应条件
1: With 1-propanephosphonic acid cyclic anhydride; N-ethyl-N,N-diisopropylamine in ethyl acetate T=0°C; 0.166667 h; 2: With sodium tetrahydroborate in water; ethyl acetate T=0°C; 0.366667 h;
参考文献
Nagendra; Madhu; Vishwanatha; Sureshbabu, Vommina V.
Tetrahedron Letters, 2012 , vol. 53, # 38 p. 5059 - 5063
反应条件
1: With 1-propanephosphonic acid cyclic anhydride; N-ethyl-N,N-diisopropylamine in ethyl acetate T=0°C; 0.166667 h; 2: With sodium tetrahydroborate in water; ethyl acetate T=0°C; 0.366667 h;
参考文献
Nagendra; Madhu; Vishwanatha; Sureshbabu, Vommina V.
Tetrahedron Letters, 2012 , vol. 53, # 38 p. 5059 - 5063
反应条件
1: dicyclohexylcarbodiimide 2: Et3N / CHCl3 / Ambient temperature View Scheme
参考文献
Arena, Giuseppe; Impellizzeri, Giuseppe; Maccarrone, Giuseppe; Pappalardo, Giuseppe; Sciotto, Domenico; Rizzarelli, Enrico
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1992 , # 3 p. 371 - 376