N-苄氧羰基-L-丙氨酸合成路线 （共 167 条）
反应条件
chloroform; triethylamine; toluene
anschliessendes Behandeln mit L-Phenylalanin-aethylester und Behandeln des Reaktionsprodukts mit wss. NaOH;
参考文献
Fu et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 6054,6057
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine; trichlorophosphate in dichloromethane
T=20°C; 2 h;
参考文献
Chen, Hu; Xu, Xunfu; Liu, Liu; Tang, Guo; Zhao, Yufen
RSC Advances, 2013 , vol. 3, # 37 p. 16247 - 16250
反应条件
N-[2-(4-sulphonatephenylamino)-4-methoxy-1,3,5-triazin-6-yl]-4-methylmorpholinium inner salt; sodium hydrogencarbonate in water
5 h; Product distribution / selectivity;
参考文献
Politechnika Lódzka
Patent: EP2407460 A1, 2012 ;
Location in patent: Page/Page column 9 ;
反应条件
1: tetrahydrofuran / 0 °C
2: 0.607 g / 4-methylmorpholine / tetrahydrofuran / 16 h / 0 - 20 °C
View Scheme
参考文献
Mital, Alka; Srivastava, Nivedita; Kumar, Arvind
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1991 , vol. 30, # 12 p. 1129 - 1130
反应条件
n-ethyl morpholine in tetrahydrofuran; N-methyl-acetamide; water
参考文献
Hoffmann-La Roche Inc.
Patent: US4176116 A1, 1979 ;
反应条件
1: 74 percent / N,N'-dicyclohexylcarbodiimide, triethylamine / CH2Cl2 / 24 h / Ambient temperature
2: 70 percent / 1 N NaOH / methanol / below 5 deg C
View Scheme
参考文献
Kemp,D.S. et al.
Tetrahedron, 1974 , vol. 30, p. 3969 - 3980
反应条件
triethylamine; dicyclohexyl-carbodiimide in tetrahydrofuran
参考文献
Stelakatos,G.C.
Journal of the American Chemical Society, 1961 , vol. 83, p. 4222 - 4224
反应条件
1: N-methylmorpholine / CH2Cl2 / 0.33 h / -15 °C
2: N-methylmorpholine / CH2Cl2 / 1 h / -15 °C
View Scheme
参考文献
Tsuboi; Okada
Chemical and pharmaceutical bulletin, 1989 , vol. 37, # 1 p. 46 - 49
反应条件
tetrachloromethane; triethylamine; triphenylphosphine in acetonitrile
参考文献
Topuzyan, V. O.; Martirosyan, M. S.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 11.2 p. 2148 - 2153
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 11 p. 2418 - 2424
反应条件
tris(p-nitrophenyl)-phosphite; triethylamine in 1,4-dioxane
参考文献
Mitin,Yu.V.; Glinskaya,O.V.
J. Gen. Chem. USSR (Engl. Transl.), 1969 , vol. 39, # 6 p. 1287 - 1260,1258 - 1260
