1: 78 percent / PhSO2Cl / pyridine / 0 - 20 °C 2: 90 percent / Pd/C / tetrahydrofuran / 4 h / 20 °C View Scheme

1: 78 percent / PhSO2Cl / pyridine / 0 - 20 °C 2: 90 percent / Pd/C / tetrahydrofuran / 4 h / 20 °C 3: 65 percent / DEAD; TPP / 0 - 20 °C View Scheme

1: 78 percent / PhSO2Cl / pyridine / 0 - 20 °C 2: 90 percent / Pd/C / tetrahydrofuran / 4 h / 20 °C View Scheme

Multi-step reaction with 2 steps 1: 78 percent / PhSO2Cl / pyridine / 0 - 20 °C2: 90 percent / Pd/C / tetrahydrofuran / 4 h / 20 °C  

With  pyridine; benzenesulfonyl chloride T=0°C; 12 h;   

With  potassium hydroxide in  methanol; hexane; methyl acetate; water; acetic acid Show Experimental Procedure  

Multi-step reaction with 4 steps 1: TiCl4 / CH2Cl2 / 0.75 h / -78 °C2: 97 percent / CF3SO3Ag / CH2Cl2 / 2 h / Ambient temperature3: 1.) LDA / 1.) THF, -50 deg C, 40 min; -30 deg C, 40 min, 2.) HMPA, -50 deg C, 1 h; -20 deg C, 2 h; 0 deg C, 1 h4: 1 N KOH / ethanol / 4 h / 50 °C