copper(l) iodide; palladium diacetate; triethylamine in tetrahydrofuran T=20°C; 6 h; Inert atmosphere;

1: With N-butylamine; copper(l) chloride in water T=0°C; Cadiot-Chodkiewicz reaction; 2: With hydroxylamine hydrochloride in water Cadiot-Chodkiewicz reaction; 0.5 h;

1: 1.) n-butyllithium, 2.) bromine / 1.) ether, hexane, -78 deg C, 1 h, 2.) ether, hexane, -78 deg C - -50 deg C 2: ethylamine, copper chloride, hydroxylamine hydrochloride / H2O; methanol / 1.) 20 deg C - 40 deg C, 1 h, 2.) RT, 1 h View Scheme

copper chloride; hydroxylamine hydrochloride; ethylamine in methanol; water 1.) 20 deg C - 40 deg C, 1 h, 2.) RT, 1 h;