N-[2-[(5-氯-2-苯并恶唑基)氨基]乙基]氨基甲酸叔丁酯合成路线 （共 2 条）
反应条件
1.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane; water; acetonitrile / 10.08 h / 20 - 40 °C 2.1: tetrahydrofuran / 5 - 60 °C 3.1: sodium acetate; sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 15 - 20 °C 4.1: tetrahydrofuran / 4.92 h / 20 °C / Resolution of racemate 4.2: 22.25 h / 20 °C / Resolution of racemate View Scheme
参考文献
Baxter, Carl A.; Cleator, Ed; Brands, Karel M. J.; Edwards, John S.; Reamer, Robert A.; Sheen, Faye J.; Stewart, Gavin W.; Strotman, Neil A.; Wallace, Debra J.
Organic Process Research and Development, 2011 , vol. 15, # 2 p. 367 - 375
反应条件
1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane; water; acetonitrile / 10.08 h / 20 - 40 °C 2: tetrahydrofuran / 5 - 60 °C 3: sodium acetate; sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 15 - 20 °C View Scheme
参考文献
Baxter, Carl A.; Cleator, Ed; Brands, Karel M. J.; Edwards, John S.; Reamer, Robert A.; Sheen, Faye J.; Stewart, Gavin W.; Strotman, Neil A.; Wallace, Debra J.
Organic Process Research and Development, 2011 , vol. 15, # 2 p. 367 - 375
