4-甲氧基苯基磷酸二乙酯合成路线 （共 39 条）
反应条件
1: 42 percent / (CH3)3COK / tetrahydrofuran / 2 h / Ambient temperature
2: 95 percent / hydrogen / Pd/C / ethyl acetate / 12 h / 760 Torr
View Scheme
参考文献
Berrier, Christian; Jacquesy, Jean-Claude; Renoux, Alain
Bulletin de la Societe Chimique de France, 1987 , # 1 p. 212 - 218
反应条件
potassium tert-butylate in tetrahydrofuran
T=0 - 20°C; Horner-Wadsworth-Emmons Olefination; 8.16667 h;
参考文献
Sakong, Chun; Kim, Hae Joong; Kim, Se Hun; Namgoong, Jin Woong; Park, Jong Ho; Ryu, Jang-Hyun; Kim, Boeun; Ko, Min Jae; Kim, Jae Pil
New Journal of Chemistry, 2012 , vol. 36, # 10 p. 2025 - 2032
反应条件
1: NaOEt / dimethylformamide; ethanol / 3 h / 20 °C
2: BBr3 / CH2Cl2 / -10 - 0 °C
View Scheme
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
sodium ethanolate in ethanol; N,N-dimethyl-formamide
T=20°C; 3 h;
参考文献
Chen, Guoliang; Shan, Wei; Wu, Yingliang; Ren, Lixiang; Dong, Jinhua; Ji, Zhizhong
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 12 p. 1587 - 1590
反应条件
1: NaH / tetrahydrofuran / 12 h / 26 °C
2: Bu4NF / tetrahydrofuran / 10 h / 27 °C
3: 15 percent / TpRu(PPh3)(CH3CN)2PF6 / toluene / 6 h / 110 °C
View Scheme
参考文献
Shen, Hung-Chin; Pal, Sitaram; Lian, Jian-Jou; Liu, Rai-Shung
Journal of the American Chemical Society, 2003 , vol. 125, # 51 p. 15762 - 15763
反应条件
1: NaH / tetrahydrofuran / 12 h / 26 °C
2: Bu4NF / tetrahydrofuran / 10 h / 27 °C
3: 6 percent / TpRu(PPh3)(CH3CN)2PF6 / toluene / 6 h / 110 °C
View Scheme
参考文献
Shen, Hung-Chin; Pal, Sitaram; Lian, Jian-Jou; Liu, Rai-Shung
Journal of the American Chemical Society, 2003 , vol. 125, # 51 p. 15762 - 15763
反应条件
1: 1.) tBuOK / 1.) 0 degC, 2.) 12 hours, ambient temperature
2: H2 / 5percent Pd/C / ethyl acetate / 12 h
View Scheme
参考文献
Berrier, C.; Jacquesy, J. C.; Gesson, J. P.; Renoux, A.
Tetrahedron, 1984 , vol. 40, # 11 p. 1983 - 1994
参考文献
Williams,A. et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1973 , p. 25 - 33
反应条件
sodium methylate in N,N-dimethyl-formamide
T=20°C; Wittig reaction; 10 h;
参考文献
Cai, Wenqing; Zhang, Liangwei; Song, Yanlin; Zhang, Baoxin; Cui, Xuemei; Hu, Guanming; Fang, Jianguo
Free Radical Research, 2011 , vol. 45, # 11-12 p. 1379 - 1387
