3-甲氧基-4-(4-甲基-1H-咪唑-1-基)苯硼酸合成路线 (共 2 条)
反应条件
n-butyllithium; tri-isopropoxy-borane in tetrahydrofuran; hexane T=-78 - 20°C; Product distribution / selectivity;
参考文献
GLAXO GROUP LIMITED
Patent: WO2009/50227 A1, 2009 ;
Location in patent: Page/Page column 78 ;
WO 2009/050227 A1
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in ethylene glycol dimethyl ether Heating / reflux; Product distribution / selectivity;
参考文献
GLAXO GROUP LIMITED
Patent: WO2009/50227 A1, 2009 ;
Location in patent: Page/Page column 19-20 ;
WO 2009/050227 A1