(2S)-2-氨基-5-[[(2R)-1-乙氧基-1-氧代-3-巯基丙-2-基]氨基]-5-氧代戊酸合成路线 （共 2 条）
反应条件
1: 63 percent / H2O 2: acetonitrile / 0.83 h / Heating 3: acetonitrile / Ambient temperature 4: 2.0 M NH2NH2*H2O, Et3N / methanol; H2O 5: 1.) Hg(OAc)2, 2.) H2S (gas) / 1.) H2O, 38-41 deg C, 2.5 h, 2.) H2O, RT, 45 min View Scheme
参考文献
Nagasawa, Herbert T.; Cohen, Jonathan F.; Holleschau, Ann M.; Rathbun, William B.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 8 p. 1676 - 1681
反应条件
hydrogen sulfide; mercury(II) diacetate 1.) H2O, 38-41 deg C, 2.5 h, 2.) H2O, RT, 45 min; Multistep reaction;
参考文献
Nagasawa, Herbert T.; Cohen, Jonathan F.; Holleschau, Ann M.; Rathbun, William B.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 8 p. 1676 - 1681
