反应条件
1: 1.) n-BuLi / 1.) THF, hexane, -78 deg C, 3 h, 2.) THF, hexane, a) -78 deg C, 15 min, b) from -78 deg C to RT, 1 h 2: 2,2,2-trifluoroethanol, tetrabutylammonium fluoride / tetrahydrofuran / 0.5 h / -78 - 20 °C View Scheme
参考文献
Chen, George T.; King, Michael; Gusovsky, Fabian; Creveling, Cyrus R.; Daly, John W.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 24 p. 3947 - 3955
