(βR)-β-环戊基-4-(4,4,5,5-四甲基-1,3,2-二氧杂硼杂环戊烷-2-基)-1H-吡唑-1-丙腈合成路线 (共 4 条)
反应条件
potassium acetate; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane T=120°C; 1 h; microwave irraddiation;
参考文献
US2010/190981 A1, ;
Page/Page column 71-72 ;
US 20100190981 A1
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium acetate in 1,4-dioxane T=120°C; 1 h; Inert atmosphereMicrowave irradiation;
参考文献
Organic Letters, , vol. 11, # 9 p. 1999 - 2002
反应条件
Chiralpak.(R). IA in hexanes; ethanol T=20°C; Purification / work up;
参考文献
US2010/190981 A1, ;
Page/Page column 91-92 ;
US 20100190981 A1
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane; water T=20 - 95°C; Inert atmosphere; Product distribution / selectivity;
参考文献
Zhou, Jiacheng; Liu, Pingli; Lin, Qiyan; Metcalf, Brian W.; Meloni, David; Pan, Yongchun; Xia, Michael; Li, Mei; Yue, Tai-Yuen; Rodgers, James D.; Wang, Haisheng
Patent: US2010/190981 A1, 2010 ;
Location in patent: Page/Page column 93-94 ;
US 20100190981 A1