(2R)-2-氨基-5,5,5-三氟-戊胺盐酸盐合成路线 (共 2 条)
反应条件
hydrogen; palladium(II) hydroxide/carbon in methanol; water T=30 - 60°C; Product distribution / selectivity;
参考文献
Bristol-Myers Squibb Company
Patent: US2010/240719 A1, 2010 ;
Location in patent: Page/Page column 10 ;
反应条件
triethylamine in tetrahydrofuran T=15 - 25°C; 0.833333 h; Product distribution / selectivity;
参考文献
Bristol-Myers Squibb Company
Patent: US2010/240719 A1, 2010 ;
Location in patent: Page/Page column 12; 13 ;