(2R)-2-[N-[(4-氯苯基)磺酰基]-N-[2-氟-4-(1,2,4-恶二唑-3-基)苄基]氨基]-5,5,5-三氟戊酰胺合成路线 （共 4 条）
反应条件
trifluoroacetic acid in acetonitrile T=40 - 50°C; Product distribution / selectivity;
参考文献
Bristol-Myers Squibb Company
Patent: US2009/111858 A1, 2009 ;
Location in patent: Page/Page column 23 ;
反应条件
hydroxylamine; tetra-(n-butyl)ammonium iodide; caesium carbonate in acetonitrile T=15 - 35°C; Product distribution / selectivity;
参考文献
Bristol-Myers Squibb Company
Patent: US2009/111858 A1, 2009 ;
Location in patent: Page/Page column 21-22 ;
反应条件
caesium carbonate in N,N-dimethyl-formamide T=20°C; 2 h; Product distribution / selectivity;
参考文献
Bristol-Myers Squibb Company
Patent: US2009/111858 A1, 2009 ;
Location in patent: Page/Page column 4; 19 ;
反应条件
in methanol; water; acetonitrile T=15 - 52°C; 4 h; Product distribution / selectivity;
参考文献
US2009/111858 A1, ;
Page/Page column 20-21 ;
