2,2,2-三氟-1-(吡嗪-2-基)乙酮合成路线 (共 1 条)
反应条件
1: With cesium fluoride in ethylene glycol dimethyl ether T=20°C; 18 h; 2: With tetrabutyl ammonium fluoride; acetic acid in tetrahydrofuran T=20°C; 3 h;
参考文献
VIROBAY, INC.
Patent: WO2009/55467 A2, 2009 ;
Location in patent: Page/Page column 44 ;
WO 2009/055467 A2